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(Biphenyl-4-yl)methylammonium Chlorides: Potent Anticonvulsants That Modulate Na(+) Currents
We have reported that compounds containing a bi-aryl linked unit (Ar-X-Ar′) modulated Na(+) currents by promoting slow inactivation and fast inactivation processes and by inducing frequency (use)-dependent inhibition of Na(+) currents. These electrophysiological properties have been associated with...
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| Glavni autori: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3842382/ https://ncbi.nlm.nih.gov/pubmed/23772678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm4007092 |
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