Φορτώνει......
Chimeric Agents Derived from the Functionalized Amino Acid, Lacosamide, and the α-Aminoamide, Safinamide: Evaluation of Their Inhibitory Actions on Voltage-Gated Sodium Channels, and Antiseizure and Antinociception Activities and Comparison with Lacosamide and Safinamide
[Image: see text] The functionalized amino acid, lacosamide ((R)-2), and the α-aminoamide, safinamide ((S)-3), are neurological agents that have been extensively investigated and have displayed potent anticonvulsant activities in seizure models. Both compounds have been reported to modulate voltage-...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | ACS Chem Neurosci |
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| Κύριοι συγγραφείς: | , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Chemical
Society
2014
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| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4372064/ https://ncbi.nlm.nih.gov/pubmed/25418676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn5002182 |
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