Nalaganje...
Merging Structural Motifs of Functionalized Amino Acids and α-Aminoamides Results in Novel Anticonvulsant Compounds with Significant Effects on Slow and Fast Inactivation of Voltage-Gated Sodium Channels and in the Treatment of Neuropathic Pain
[Image: see text] We recently reported that merging key structural pharmacophores of the anticonvulsant drugs lacosamide (a functionalized amino acid) with safinamide (an α-aminoamide) resulted in novel compounds with anticonvulsant activities superior to that of either drug alone. Here, we examined...
Shranjeno v:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Chemical Society
2011
|
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3134314/ https://ncbi.nlm.nih.gov/pubmed/21765969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn200024z |
| Oznake: |
Označite
Brez oznak, prvi označite!
|