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Merging the Structural Motifs of Functionalized Amino Acids and α-Aminoamides: Compounds with Significant Anticonvulsant Activities

Functional amino acids (FAAs) and α-aminoamides (AAAs) are two classes of antiepileptic drugs (AEDs) that exhibit pronounced anticonvulsant activities. We combined key structural pharmacophores present in FAAs and AAAs to generate a new series of compounds and document that select compounds exhibit...

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Bibliografiset tiedot
Päätekijät: Salomé, Christophe, Salomé-Grosjean, Elise, Stables, James P., Kohn, Harold
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867451/
https://ncbi.nlm.nih.gov/pubmed/20394379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm100185c
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