Antiretroviral Efficacy and Pharmacokinetics of Oral Bis(isopropyloxycarbonyloxymethyl)9-(2-Phosphonylmethoxypropyl)adenine in Mice

Por Naesens, Lieve, Bischofberger, Norbert, Augustijns, Patrick, Annaert, Pieter, Van den Mooter, Guy, Arimilli, Murty N., Kim, Choung U., De Clercq, Erik
Publicado em 1998

Characterization of Human Influenza Virus Variants Selected In Vitro in the Presence of the Neuraminidase Inhibitor GS 4071

Por Tai, Chun Y., Escarpe, Paul A., Sidwell, Robert W., Williams, Matthew A., Lew, Willard, Wu, Huiwei, Kim, Choung U., Mendel, Dirk B.
Publicado em 1998

Preclinical Evaluation of GS-9160, a Novel Inhibitor of Human Immunodeficiency Virus Type 1 Integrase

Por Jones, Gregg S., Yu, Fang, Zeynalzadegan, Ameneh, Hesselgesser, Joseph, Chen, Xiaowu, Chen, James, Jin, Haolun, Kim, Choung U., Wright, Matthew, Geleziunas, Romas, Tsiang, Manuel
Publicado em 2009

Metabolism and Pharmacokinetics of the Anti-Hepatitis C Virus Nucleotide Prodrug GS-6620

Por Murakami, Eisuke, Wang, Ting, Babusis, Darius, Lepist, Eve-Irene, Sauer, Dorothea, Park, Yeojin, Vela, Jennifer E., Shih, Robert, Birkus, Gabriel, Stefanidis, Dimitrios, Kim, Choung U., Cho, Aesop, Ray, Adrian S.
Publicado em 2014

Identification of GS 4104 as an Orally Bioavailable Prodrug of the Influenza Virus Neuraminidase Inhibitor GS 4071

Por Li, Weixing, Escarpe, Paul A., Eisenberg, Eugene J., Cundy, Kenneth C., Sweet, Clive, Jakeman, Kenneth J., Merson, James, Lew, Willard, Williams, Matt, Zhang, Lijun, Kim, Choung U., Bischofberger, Norbert, Chen, Ming S., Mendel, Dirk B.
Publicado em 1998

Preclinical Characterization of the Novel Hepatitis C Virus NS3 Protease Inhibitor GS-9451

Por Yang, Huiling, Robinson, Margaret, Corsa, Amoreena C., Peng, Betty, Cheng, Guofeng, Tian, Yang, Wang, Yujin, Pakdaman, Rowchanak, Shen, Marian, Qi, Xiaoping, Mo, Hongmei, Tay, Chin, Krawczyk, Steve, Sheng, X. Christopher, Kim, Choung U., Yang, Chris, Delaney, William E.
Publicado em 2014

Oral Administration of a Prodrug of the Influenza Virus Neuraminidase Inhibitor GS 4071 Protects Mice and Ferrets against Influenza Infection

Por Mendel, Dirk B., Tai, Chun Y., Escarpe, Paul A., Li, Weixing, Sidwell, Robert W., Huffman, John H., Sweet, Clive, Jakeman, Kenneth J., Merson, James, Lacy, Steven A., Lew, Willard, Williams, Matthew A., Zhang, Lijun, Chen, Ming S., Bischofberger, Norbert, Kim, Choung U.
Publicado em 1998

Inhibition of Hepatitis C Virus Replication by GS-6620, a Potent C-Nucleoside Monophosphate Prodrug

Por Feng, Joy Y., Cheng, Guofeng, Perry, Jason, Barauskas, Ona, Xu, Yili, Fenaux, Martijn, Eng, Stacey, Tirunagari, Neeraj, Peng, Betty, Yu, Mei, Tian, Yang, Lee, Yu-Jen, Stepan, George, Lagpacan, Leanna L., Jin, Debi, Hung, Magdeleine, Ku, Karin S., Han, Bin, Kitrinos, Kathryn, Perron, Michel, Birkus, Gabriel, Wong, Kelly A., Zhong, Weidong, Kim, Choung U., Carey, Anne, Cho, Aesop, Ray, Adrian S.
Publicado em 2014