Novel Nucleotide Human Immunodeficiency Virus Reverse Transcriptase Inhibitor GS-9148 with a Low Nephrotoxic Potential: Characterization of Renal Transport and Accumulation

Por Cihlar, Tomas, LaFlamme, Genevieve, Fisher, Robyn, Carey, Anne C., Vela, Jennifer E., Mackman, Richard, Ray, Adrian S.
Publicado em 2009

Nucleotide Analog Prodrug, Tenofovir Disoproxil, Enhances Lymphoid Cell Loading Following Oral Administration in Monkeys

Por Durand-Gasselin, Lucie, Van Rompay, Koen K.A., Vela, Jennifer E., Henne, Ilana N., Lee, William A., Rhodes, Gerry R., Ray, Adrian S.
Publicado em 2009

Mechanism of Active Renal Tubular Efflux of Tenofovir

Por Ray, Adrian S., Cihlar, Tomas, Robinson, Kelly L., Tong, Leah, Vela, Jennifer E., Fuller, Michael D., Wieman, Lani M., Eisenberg, Eugene J., Rhodes, Gerry R.
Publicado em 2006

Intracellular Metabolism of the Nucleotide Prodrug GS-9131, a Potent Anti-Human Immunodeficiency Virus Agent

Por Ray, Adrian S., Vela, Jennifer E., Boojamra, Constantine G., Zhang, Lijun, Hui, Hon, Callebaut, Christian, Stray, Kirsten, Lin, Kuei-Ying, Gao, Ying, Mackman, Richard L., Cihlar, Tomas
Publicado em 2008

Metabolism and Pharmacokinetics of the Anti-Hepatitis C Virus Nucleotide Prodrug GS-6620

Por Murakami, Eisuke, Wang, Ting, Babusis, Darius, Lepist, Eve-Irene, Sauer, Dorothea, Park, Yeojin, Vela, Jennifer E., Shih, Robert, Birkus, Gabriel, Stefanidis, Dimitrios, Kim, Choung U., Cho, Aesop, Ray, Adrian S.
Publicado em 2014

Design and Profiling of GS-9148, a Novel Nucleotide Analog Active against Nucleoside-Resistant Variants of Human Immunodeficiency Virus Type 1, and Its Orally Bioavailable Phosphon...

Por Cihlar, Tomas, Ray, Adrian S., Boojamra, Constantine G., Zhang, Lijun, Hui, Hon, Laflamme, Genevieve, Vela, Jennifer E., Grant, Deborah, Chen, James, Myrick, Florence, White, Kirsten L., Gao, Ying, Lin, Kuei-Ying, Douglas, Janet L., Parkin, Neil T., Carey, Anne, Pakdaman, Rowchanak, Mackman, Richard L.
Publicado em 2008

Sensitivity of Mitochondrial Transcription and Resistance of RNA Polymerase II Dependent Nuclear Transcription to Antiviral Ribonucleosides

Por Arnold, Jamie J., Sharma, Suresh D., Feng, Joy Y., Ray, Adrian S., Smidansky, Eric D., Kireeva, Maria L., Cho, Aesop, Perry, Jason, Vela, Jennifer E., Park, Yeojin, Xu, Yili, Tian, Yang, Babusis, Darius, Barauskus, Ona, Peterson, Blake R., Gnatt, Averell, Kashlev, Mikhail, Zhong, Weidong, Cameron, Craig E.
Publicado em 2012