Mechanism of Active Renal Tubular Efflux of Tenofovir

Tenofovir (TFV) undergoes renal elimination by a combination of glomerular filtration and active tubular secretion. While transporter-mediated uptake of TFV from the blood into proximal-tubule cells has been well characterized, comparatively little is known about the efflux system responsible for tr...

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Detalhes bibliográficos
Main Authors: Ray, Adrian S., Cihlar, Tomas, Robinson, Kelly L., Tong, Leah, Vela, Jennifer E., Fuller, Michael D., Wieman, Lani M., Eisenberg, Eugene J., Rhodes, Gerry R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1610069/
https://ncbi.nlm.nih.gov/pubmed/17005808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00251-06
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