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Assessment of Mitochondrial Toxicity in Human Cells Treated with Tenofovir: Comparison with Other Nucleoside Reverse Transcriptase Inhibitors

Drug-associated dysfunction of mitochondria is believed to play a role in the etiology of the various adverse symptoms that occur in human immunodeficiency virus (HIV)-infected patients treated with the nucleoside reverse transcriptase inhibitors (NRTIs). Tenofovir, a nucleotide analog recently appr...

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Hlavní autoři: Birkus, Gabriel, Hitchcock, Michael J. M., Cihlar, Tomas
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC127499/
https://ncbi.nlm.nih.gov/pubmed/11850253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.3.716-723.2002
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