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Assessment of Mitochondrial Toxicity in Human Cells Treated with Tenofovir: Comparison with Other Nucleoside Reverse Transcriptase Inhibitors

Drug-associated dysfunction of mitochondria is believed to play a role in the etiology of the various adverse symptoms that occur in human immunodeficiency virus (HIV)-infected patients treated with the nucleoside reverse transcriptase inhibitors (NRTIs). Tenofovir, a nucleotide analog recently appr...

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Detalhes bibliográficos
Main Authors: Birkus, Gabriel, Hitchcock, Michael J. M., Cihlar, Tomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127499/
https://ncbi.nlm.nih.gov/pubmed/11850253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.3.716-723.2002
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