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Assessment of Mitochondrial Toxicity in Human Cells Treated with Tenofovir: Comparison with Other Nucleoside Reverse Transcriptase Inhibitors

Drug-associated dysfunction of mitochondria is believed to play a role in the etiology of the various adverse symptoms that occur in human immunodeficiency virus (HIV)-infected patients treated with the nucleoside reverse transcriptase inhibitors (NRTIs). Tenofovir, a nucleotide analog recently appr...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Birkus, Gabriel, Hitchcock, Michael J. M., Cihlar, Tomas
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2002
Fag:
Antiviral Agents
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127499/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11850253/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.3.716-723.2002
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