Identification of GS 4104 as an Orally Bioavailable Prodrug of the Influenza Virus Neuraminidase Inhibitor GS 4071

GS 4071 is a potent carbocyclic transition-state analog inhibitor of influenza virus neuraminidase with activity against both influenza A and B viruses in vitro. GS 4116, the guanidino analog of GS 4071, is a 10-fold more potent inhibitor of influenza virus replication in tissue culture than GS 4071...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Li, Weixing, Escarpe, Paul A., Eisenberg, Eugene J., Cundy, Kenneth C., Sweet, Clive, Jakeman, Kenneth J., Merson, James, Lew, Willard, Williams, Matt, Zhang, Lijun, Kim, Choung U., Bischofberger, Norbert, Chen, Ming S., Mendel, Dirk B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC105512/
https://ncbi.nlm.nih.gov/pubmed/9517946
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados