Characterization of Human Influenza Virus Variants Selected In Vitro in the Presence of the Neuraminidase Inhibitor GS 4071

An oral prodrug of GS 4071, a potent and selective inhibitor of influenza neuraminidases, is currently under clinical development for the treatment and prophylaxis of influenza virus infections in humans. To investigate the potential development of resistance during the clinical use of this compound...

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Detalhes bibliográficos
Main Authors: Tai, Chun Y., Escarpe, Paul A., Sidwell, Robert W., Williams, Matthew A., Lew, Willard, Wu, Huiwei, Kim, Choung U., Mendel, Dirk B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC106027/
https://ncbi.nlm.nih.gov/pubmed/9835519
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