Characterization of Human Influenza Virus Variants Selected In Vitro in the Presence of the Neuraminidase Inhibitor GS 4071

An oral prodrug of GS 4071, a potent and selective inhibitor of influenza neuraminidases, is currently under clinical development for the treatment and prophylaxis of influenza virus infections in humans. To investigate the potential development of resistance during the clinical use of this compound...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Tai, Chun Y., Escarpe, Paul A., Sidwell, Robert W., Williams, Matthew A., Lew, Willard, Wu, Huiwei, Kim, Choung U., Mendel, Dirk B.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1998
Schlagworte:	Antiviral Agents
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC106027/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9835519/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.12.3234
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