In Vitro Virology Profile of Tenofovir Alafenamide, a Novel Oral Prodrug of Tenofovir with Improved Antiviral Activity Compared to That of Tenofovir Disoproxil Fumarate

Por Callebaut, Christian, Stepan, George, Tian, Yang, Miller, Michael D.
Publicado no Antimicrob Agents Chemother (2015)

Search for small molecule activators of latent HIV

Por Geleziunas, Romas, Stepan, George, Wei, George, Yu, Helen, Graupe, Michael, Pagratis, Nikos, Barnes, Tiffany, Cihlar, Tomas, Hesselgesser, Joe
Publicado em 2012

Role of Mitochondrial RNA Polymerase in the Toxicity of Nucleotide Inhibitors of Hepatitis C Virus

Por Feng, Joy Y., Xu, Yili, Barauskas, Ona, Perry, Jason K., Ahmadyar, Shekeba, Stepan, George, Yu, Helen, Babusis, Darius, Park, Yeojin, McCutcheon, Krista, Perron, Michel, Schultz, Brian E., Sakowicz, Roman, Ray, Adrian S.
Publicado no Antimicrob Agents Chemother (2016)

Study of Marine Natural Products Including Resorcyclic Acid Lactones from Humicola fuscoatra That Reactivate Latent HIV-1 Expression in an in Vitro Model of Central Memory CD4+ T C...

Por Mejia, Eric J., Loveridge, Steven T., Stepan, George, Tsai, Angela, Jones, Gregg S., Barnes, Tiffany, White, Kimberly N., Drašković, Marija, Tenney, Karen, Tsiang, Manuel, Geleziunas, Romas, Cihlar, Tomas, Pagratis, Nikos, Tian, Yang, Yu, Helen, Crews, Phillip
Publicado em 2014

Abyssomicin 2 Reactivates Latent HIV-1 by a PKC- and HDAC-Independent Mechanism

Por León, Brian, Navarro, Gabriel, Dickey, Bailey J., Stepan, George, Tsai, Angela, Jones, Gregg S., Morales, Monica E., Barnes, Tiffany, Ahmadyar, Shekeba, Tsiang, Manuel, Geleziunas, Romas, Cihlar, Tomas, Pagratis, Nikos, Tian, Yang, Yu, Helen, Linington, Roger G.
Publicado no Org Lett (2015)

Antiviral Activity of Bictegravir (GS-9883), a Novel Potent HIV-1 Integrase Strand Transfer Inhibitor with an Improved Resistance Profile

Por Tsiang, Manuel, Jones, Gregg S., Goldsmith, Joshua, Mulato, Andrew, Hansen, Derek, Kan, Elaine, Tsai, Luong, Bam, Rujuta A., Stepan, George, Stray, Kirsten M., Niedziela-Majka, Anita, Yant, Stephen R., Yu, Helen, Kukolj, George, Cihlar, Tomas, Lazerwith, Scott E., White, Kirsten L., Jin, Haolun
Publicado no Antimicrob Agents Chemother (2016)

Histone Deacetylase Inhibitor Romidepsin Induces HIV Expression in CD4 T Cells from Patients on Suppressive Antiretroviral Therapy at Concentrations Achieved by Clinical Dosing

Por Wei, Datsen George, Chiang, Vicki, Fyne, Elizabeth, Balakrishnan, Mini, Barnes, Tiffany, Graupe, Michael, Hesselgesser, Joseph, Irrinki, Alivelu, Murry, Jeffrey P., Stepan, George, Stray, Kirsten M., Tsai, Angela, Yu, Helen, Spindler, Jonathan, Kearney, Mary, Spina, Celsa A., McMahon, Deborah, Lalezari, Jacob, Sloan, Derek, Mellors, John, Geleziunas, Romas, Cihlar, Tomas
Publicado em 2014

Inhibition of Hepatitis C Virus Replication by GS-6620, a Potent C-Nucleoside Monophosphate Prodrug

Por Feng, Joy Y., Cheng, Guofeng, Perry, Jason, Barauskas, Ona, Xu, Yili, Fenaux, Martijn, Eng, Stacey, Tirunagari, Neeraj, Peng, Betty, Yu, Mei, Tian, Yang, Lee, Yu-Jen, Stepan, George, Lagpacan, Leanna L., Jin, Debi, Hung, Magdeleine, Ku, Karin S., Han, Bin, Kitrinos, Kathryn, Perron, Michel, Birkus, Gabriel, Wong, Kelly A., Zhong, Weidong, Kim, Choung U., Carey, Anne, Cho, Aesop, Ray, Adrian S.
Publicado em 2014