Inhibitors of Histone Deacetylases: CORRELATION BETWEEN ISOFORM SPECIFICITY AND REACTIVATION OF HIV TYPE 1 (HIV-1) FROM LATENTLY INFECTED CELLS

Por Huber, Kelly, Doyon, Geneviève, Plaks, Joseph, Fyne, Elizabeth, Mellors, John W., Sluis-Cremer, Nicolas
Publicado em 2011

Quantification of HIV-1 latency reversal in resting CD4(+) T cells from patients on suppressive antiretroviral therapy

Por Cillo, Anthony R., Sobolewski, Michele D., Bosch, Ronald J., Fyne, Elizabeth, Piatak, Michael, Coffin, John M., Mellors, John W.
Publicado em 2014

Novel Assays for Measurement of Total Cell-Associated HIV-1 DNA and RNA

Por Hong, Feiyu, Aga, Evgenia, Cillo, Anthony R., Yates, Aarika L., Besson, Guillaume, Fyne, Elizabeth, Koontz, Dianna L., Jennings, Cheryl, Zheng, Lu, Mellors, John W.
Publicado no J Clin Microbiol (2016)

Improved Single-Copy Assays for Quantification of Persistent HIV-1 Viremia in Patients on Suppressive Antiretroviral Therapy

Por Cillo, Anthony R., Vagratian, David, Bedison, Margaret A., Anderson, Elizabeth M., Kearney, Mary F., Fyne, Elizabeth, Koontz, Dianna, Coffin, John M., Piatak, Michael, Mellors, John W.
Publicado no J Clin Microbiol (2014)

Ex vivo activation of CD4(+) T-cells from donors on suppressive ART can lead to sustained production of infectious HIV-1 from a subset of infected cells

Por Bui, John K., Halvas, Elias K., Fyne, Elizabeth, Sobolewski, Michele D., Koontz, Dianna, Shao, Wei, Luke, Brian, Hong, Feiyu F., Kearney, Mary F., Mellors, John W.
Publicado no PLoS Pathog (2017)

Histone Deacetylase Inhibitor Romidepsin Induces HIV Expression in CD4 T Cells from Patients on Suppressive Antiretroviral Therapy at Concentrations Achieved by Clinical Dosing

Por Wei, Datsen George, Chiang, Vicki, Fyne, Elizabeth, Balakrishnan, Mini, Barnes, Tiffany, Graupe, Michael, Hesselgesser, Joseph, Irrinki, Alivelu, Murry, Jeffrey P., Stepan, George, Stray, Kirsten M., Tsai, Angela, Yu, Helen, Spindler, Jonathan, Kearney, Mary, Spina, Celsa A., McMahon, Deborah, Lalezari, Jacob, Sloan, Derek, Mellors, John, Geleziunas, Romas, Cihlar, Tomas
Publicado em 2014

Clonally expanded CD4(+) T cells can produce infectious HIV-1 in vivo

Por Simonetti, Francesco R., Sobolewski, Michele D., Fyne, Elizabeth, Shao, Wei, Spindler, Jonathan, Hattori, Junko, Anderson, Elizabeth M., Watters, Sarah A., Hill, Shawn, Wu, Xiaolin, Wells, David, Su, Li, Luke, Brian T., Halvas, Elias K., Besson, Guillaume, Penrose, Kerri J., Yang, Zhiming, Kwan, Richard W., Van Waes, Carter, Uldrick, Thomas, Citrin, Deborah E., Kovacs, Joseph, Polis, Michael A., Rehm, Catherine A., Gorelick, Robert, Piatak, Michael, Keele, Brandon F., Kearney, Mary F., Coffin, John M., Hughes, Stephen H., Mellors, John W., Maldarelli, Frank
Publicado no Proc Natl Acad Sci U S A (2016)