Review: influence of ART on HIV genetics

Por Simonetti, Francesco R., Kearney, Mary F.
Publicado no Curr Opin HIV AIDS (2015)

Estimate of effective recombination rate and average selection coefficient for HIV in chronic infection

Por Batorsky, Rebecca, Kearney, Mary F., Palmer, Sarah E., Maldarelli, Frank, Rouzine, Igor M., Coffin, John M.
Publicado em 2011

PAPNC, a novel method to calculate nucleotide diversity from large scale next generation sequencing data

Por Shao, Wei, Kearney, Mary F., Boltz, Valerie F., Spindler, Jonathan E., Mellors, John W., Maldarelli, Frank, Coffin, John M.
Publicado em 2014

Ultrasensitive Allele-Specific PCR Reveals Rare Preexisting Drug-Resistant Variants and a Large Replicating Virus Population in Macaques Infected with a Simian Immunodeficiency Vir...

Por Boltz, Valerie F., Ambrose, Zandrea, Kearney, Mary F., Shao, Wei, KewalRamani, Vineet N., Maldarelli, Frank, Mellors, John W., Coffin, John M.
Publicado em 2012

Limited Nucleotide Changes in the Rev Response Element (RRE) during HIV-1 Infection Alter Overall Rev-RRE Activity and Rev Multimerization

Por Sloan, Emily A., Kearney, Mary F., Gray, Laurie R., Anastos, Kathryn, Daar, Eric S., Margolick, Joseph, Maldarelli, Frank, Hammarskjold, Marie-Louise, Rekosh, David
Publicado em 2013

Retrovirus Integration Database (RID): a public database for retroviral insertion sites into host genomes

Por Shao, Wei, Shan, Jigui, Kearney, Mary F., Wu, Xiaolin, Maldarelli, Frank, Mellors, John W., Luke, Brian, Coffin, John M., Hughes, Stephen H.
Publicado no Retrovirology (2016)

Ultrasensitive single-genome sequencing: accurate, targeted, next generation sequencing of HIV-1 RNA

Por Boltz, Valerie F., Rausch, Jason, Shao, Wei, Hattori, Junko, Luke, Brian, Maldarelli, Frank, Mellors, John W., Kearney, Mary F., Coffin, John M.
Publicado no Retrovirology (2016)

Origin of Rebound Plasma HIV Includes Cells with Identical Proviruses That Are Transcriptionally Active before Stopping of Antiretroviral Therapy

Por Kearney, Mary F., Wiegand, Ann, Shao, Wei, Coffin, John M., Mellors, John W., Lederman, Michael, Gandhi, Rajesh T., Keele, Brandon F., Li, Jonathan Z.
Publicado no J Virol (2016)

Connection Subdomain Mutations in HIV-1 Subtype-C Treatment-Experienced Patients Enhance NRTI and NNRTI Drug Resistance

Por Delviks-Frankenberry, Krista A., Lengruber, Renan B., Santos, Andre F., Silveira, Jussara M., Soares, Marcelo A., Kearney, Mary F., Maldarelli, Frank, Pathak, Vinay K.
Publicado em 2012

Improved Single-Copy Assays for Quantification of Persistent HIV-1 Viremia in Patients on Suppressive Antiretroviral Therapy

Por Cillo, Anthony R., Vagratian, David, Bedison, Margaret A., Anderson, Elizabeth M., Kearney, Mary F., Fyne, Elizabeth, Koontz, Dianna, Coffin, John M., Piatak, Michael, Mellors, John W.
Publicado no J Clin Microbiol (2014)

Well-mixed plasma and tissue viral populations in RT-SHIV-infected macaques implies a lack of viral replication in the tissues during antiretroviral therapy

Por Kearney, Mary F., Anderson, Elizabeth M., Coomer, Charles, Smith, Luke, Shao, Wei, Johnson, Nicholas, Kline, Christopher, Spindler, Jonathan, Mellors, John W., Coffin, John M., Ambrose, Zandrea
Publicado no Retrovirology (2015)

Ex vivo activation of CD4(+) T-cells from donors on suppressive ART can lead to sustained production of infectious HIV-1 from a subset of infected cells

Por Bui, John K., Halvas, Elias K., Fyne, Elizabeth, Sobolewski, Michele D., Koontz, Dianna, Shao, Wei, Luke, Brian, Hong, Feiyu F., Kearney, Mary F., Mellors, John W.
Publicado no PLoS Pathog (2017)

Analysis of 454 sequencing error rate, error sources, and artifact recombination for detection of Low-frequency drug resistance mutations in HIV-1 DNA

Por Shao, Wei, Boltz, Valerie F, Spindler, Jonathan E, Kearney, Mary F, Maldarelli, Frank, Mellors, John W, Stewart, Claudia, Volfovsky, Natalia, Levitsky, Alexander, Stephens, Robert M, Coffin, John M
Publicado em 2013

Lack of Detectable HIV-1 Molecular Evolution during Suppressive Antiretroviral Therapy

Por Kearney, Mary F., Spindler, Jonathan, Shao, Wei, Yu, Sloane, Anderson, Elizabeth M., O'Shea, Angeline, Rehm, Catherine, Poethke, Carry, Kovacs, Nicholas, Mellors, John W., Coffin, John M., Maldarelli, Frank
Publicado em 2014

Multiple Sources of Contamination in Samples from Patients Reported to Have XMRV Infection

Por Kearney, Mary F., Spindler, Jonathan, Wiegand, Ann, Shao, Wei, Anderson, Elizabeth M., Maldarelli, Frank, Ruscetti, Francis W., Mellors, John W., Hughes, Steve H., Le Grice, Stuart F. J., Coffin, John M.
Publicado em 2012

Therapeutic Vaccination With Dendritic Cells Loaded With Autologous HIV Type 1–Infected Apoptotic Cells

Por Macatangay, Bernard J. C., Riddler, Sharon A., Wheeler, Nicole D., Spindler, Jonathan, Lawani, Mariam, Hong, Feiyu, Buffo, Mary J., Whiteside, Theresa L., Kearney, Mary F., Mellors, John W., Rinaldo, Charles R.
Publicado no J Infect Dis (2016)

Proviruses with identical sequences comprise a large fraction of the replication-competent HIV reservoir

Por Bui, John K., Sobolewski, Michele D., Keele, Brandon F., Spindler, Jonathan, Musick, Andrew, Wiegand, Ann, Luke, Brian T., Shao, Wei, Hughes, Stephen H., Coffin, John M., Kearney, Mary F., Mellors, John W.
Publicado no PLoS Pathog (2017)

Majority of CD4(+) T cells from peripheral blood of HIV-1–infected individuals contain only one HIV DNA molecule

Por Josefsson, Lina, King, Martin S., Makitalo, Barbro, Brännström, Johan, Shao, Wei, Maldarelli, Frank, Kearney, Mary F., Hu, Wei-Shau, Chen, Jianbo, Gaines, Hans, Mellors, John W., Albert, Jan, Coffin, John M., Palmer, Sarah E.
Publicado em 2011

Immediate antiviral therapy appears to restrict resting CD4(+) cell HIV-1 infection without accelerating the decay of latent infection

Por Archin, Nancie M., Vaidya, Naveen K., Kuruc, JoAnn D., Liberty, Abigail L., Wiegand, Ann, Kearney, Mary F., Cohen, Myron S., Coffin, John M., Bosch, Ronald J., Gay, Cynthia L., Eron, Joseph J., Margolis, David M., Perelson, Alan S.
Publicado em 2012

HIV-1 Expression Within Resting CD4(+) T Cells After Multiple Doses of Vorinostat

Por Archin, Nancy M., Bateson, Rosalie, Tripathy, Manoj K., Crooks, Amanda M., Yang, Kuo-Hsiung, Dahl, Noelle P., Kearney, Mary F., Anderson, Elizabeth M., Coffin, John M., Strain, Matthew C., Richman, Douglas D., Robertson, Kevin R., Kashuba, Angela D., Bosch, Ronald J., Hazuda, Daria J., Kuruc, Joann D., Eron, Joseph J., Margolis, David M.
Publicado em 2014