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A12 Modeling residual HIV replication and the emergence of drug resistance on ART

There are conflicting reports regarding the presence of low-level HIV replication during suppressive antiretroviral therapy (ART). We simulated varying levels of replication and estimated the number of generations needed to obtain linked, drug resistance mutations to explore the effects of replicati...

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Bibliografiske detaljer
Udgivet i:Virus Evol
Main Authors: Michael Bale, J, Valerie Boltz, F, Mellors, John W, Coffin, John M, Hughes, Stephen H, Kearney, Mary F
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735930/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ve/vez002.011
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