CpG Methylation Profiles of HIV-1 Proviral DNA in Individuals on ART

The latent HIV-1 reservoir is comprised of stably integrated and intact proviruses with limited to no viral transcription. It has been proposed that latent infection may be maintained by methylation of pro-viral DNA. Here, for the first time, we investigate the cytosine methylation of a replication...

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Veröffentlicht in:Viruses
Hauptverfasser: Boltz, Valerie F., Ceriani, Cristina, Rausch, Jason W., Shao, Wei, Bale, Michael J., Keele, Brandon F., Hoh, Rebecca, Milush, Jeffrey M., Deeks, Steve G., Maldarelli, Frank, Kearney, Mary F., Coffin, John M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8146454/
https://ncbi.nlm.nih.gov/pubmed/33946976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13050799
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