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Predicting aberrant CpG island methylation

Epigenetic silencing associated with aberrant methylation of promoter region CpG islands is one mechanism leading to loss of tumor suppressor function in human cancer. Profiling of CpG island methylation indicates that some genes are more frequently methylated than others, and that each tumor type i...

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Detalhes bibliográficos
Main Authors: Feltus, F. A., Lee, E. K., Costello, J. F., Plass, C., Vertino, P. M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC218745/
https://ncbi.nlm.nih.gov/pubmed/14519846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2037852100
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