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Predicting aberrant CpG island methylation

Epigenetic silencing associated with aberrant methylation of promoter region CpG islands is one mechanism leading to loss of tumor suppressor function in human cancer. Profiling of CpG island methylation indicates that some genes are more frequently methylated than others, and that each tumor type i...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Feltus, F. A., Lee, E. K., Costello, J. F., Plass, C., Vertino, P. M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC218745/
https://ncbi.nlm.nih.gov/pubmed/14519846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2037852100
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