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Predicting aberrant CpG island methylation
Epigenetic silencing associated with aberrant methylation of promoter region CpG islands is one mechanism leading to loss of tumor suppressor function in human cancer. Profiling of CpG island methylation indicates that some genes are more frequently methylated than others, and that each tumor type i...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC218745/ https://ncbi.nlm.nih.gov/pubmed/14519846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2037852100 |
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