Distinct genetic profiles in colorectal tumors with or without the CpG island methylator phenotype

Colorectal cancers (CRCs) are characterized by multiple genetic (mutations) and epigenetic (CpG island methylation) alterations, but it is not known whether these evolve independently through stochastic processes. We have recently described a novel pathway termed CpG island methylator phenotype (CIM...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Toyota, Minoru, Ohe-Toyota, Mutsumi, Ahuja, Nita, Issa, Jean-Pierre J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15395/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10639144/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.2.710
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