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A12 Modeling residual HIV replication and the emergence of drug resistance on ART

There are conflicting reports regarding the presence of low-level HIV replication during suppressive antiretroviral therapy (ART). We simulated varying levels of replication and estimated the number of generations needed to obtain linked, drug resistance mutations to explore the effects of replicati...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Virus Evol
Hauptverfasser: Michael Bale, J, Valerie Boltz, F, Mellors, John W, Coffin, John M, Hughes, Stephen H, Kearney, Mary F
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735930/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ve/vez002.011
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