Ultrasensitive single-genome sequencing: accurate, targeted, next generation sequencing of HIV-1 RNA

BACKGROUND: Although next generation sequencing (NGS) offers the potential for studying virus populations in unprecedented depth, PCR error, amplification bias and recombination during library construction have limited its use to population sequencing and measurements of unlinked allele frequencies....

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Detalhes bibliográficos
Publicado no:Retrovirology
Main Authors: Boltz, Valerie F., Rausch, Jason, Shao, Wei, Hattori, Junko, Luke, Brian, Maldarelli, Frank, Mellors, John W., Kearney, Mary F., Coffin, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5175307/
https://ncbi.nlm.nih.gov/pubmed/27998286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-016-0321-6
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