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PAPNC, a novel method to calculate nucleotide diversity from large scale next generation sequencing data

Estimating viral diversity in infected patients can provide insight into pathogen evolution and emergence of drug resistance. With the widespread adoption of deep sequencing, it is important to develop tools to accurately calculate population diversity from very large datasets. Current methods for e...

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Bibliografiske detaljer
Main Authors: Shao, Wei, Kearney, Mary F., Boltz, Valerie F., Spindler, Jonathan E., Mellors, John W., Maldarelli, Frank, Coffin, John M.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104926/
https://ncbi.nlm.nih.gov/pubmed/24681054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2014.03.008
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