Genetic Diversity of Simian Immunodeficiency Virus Encoding HIV-1 Reverse Transcriptase Persists in Macaques despite Antiretroviral Therapy

The impact of antiretroviral therapy (ART) on the genetics of simian immunodeficiency virus (SIV) or human immunodeficiency virus (HIV) populations has been incompletely characterized. We analyzed SIV genetic variation before, during, and after ART in a macaque model. Six pigtail macaques were infec...

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Bibliographic Details
Main Authors: Kearney, Mary, Spindler, Jon, Shao, Wei, Maldarelli, Frank, Palmer, Sarah, Hu, Shiu-Lok, Lifson, Jeffrey D., KewalRamani, Vineet N., Mellors, John W., Coffin, John M., Ambrose, Zandrea
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2011
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019993/
https://ncbi.nlm.nih.gov/pubmed/21084490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01701-10
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