RT-SHIV subpopulation dynamics in infected macaques during anti-HIV therapy

BACKGROUND: To study the dynamics of wild-type and drug-resistant HIV-1 RT variants, we developed a methodology that follows the fates of individual genomes over time within the viral quasispecies. Single genome sequences were obtained from 3 pigtail macaques infected with a recombinant simian immun...

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Detalhes bibliográficos
Main Authors: Shao, Wei, Kearney, Mary, Maldarelli, Frank, Mellors, John W, Stephens, Robert M, Lifson, Jeffrey D, KewalRamani, Vineet N, Ambrose, Zandrea, Coffin, John M, Palmer, Sarah E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776578/
https://ncbi.nlm.nih.gov/pubmed/19889213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-6-101
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