Well-mixed plasma and tissue viral populations in RT-SHIV-infected macaques implies a lack of viral replication in the tissues during antiretroviral therapy

BACKGROUND: Determining the anatomic compartments that contribute to plasma HIV-1 is critical to understanding the sources of residual viremia during combination antiretroviral therapy (ART). We analyzed viral DNA and RNA populations in the plasma and tissues from macaques infected with SIV containi...

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Detalhes bibliográficos
Publicado no:Retrovirology
Main Authors: Kearney, Mary F., Anderson, Elizabeth M., Coomer, Charles, Smith, Luke, Shao, Wei, Johnson, Nicholas, Kline, Christopher, Spindler, Jonathan, Mellors, John W., Coffin, John M., Ambrose, Zandrea
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642622/
https://ncbi.nlm.nih.gov/pubmed/26559632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-015-0212-2
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