Enhanced Antiretroviral Therapy in Rhesus Macaques Improves RT-SHIV Viral Decay Kinetics

Using an established nonhuman primate model, rhesus macaques were infected intravenously with a chimeric simian immunodeficiency virus (SIV) consisting of SIV(mac239) with the human immunodeficiency virus type 1 (HIV-1) reverse transcriptase from clone HXBc2 (RT-SHIV). The impacts of two enhanced (f...

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Bibliographische Detailangaben
Hauptverfasser: North, Thomas W., Villalobos, Andradi, Hurwitz, Selwyn J., Deere, Jesse D., Higgins, Joanne, Chatterjee, Payel, Tao, Sijia, Kauffman, Robert C., Luciw, Paul A., Kohler, James J., Schinazi, Raymond F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068512/
https://ncbi.nlm.nih.gov/pubmed/24777106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02522-14
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