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Variation of Human Immunodeficiency Virus Type-1 Reverse Transcriptase within the Simian Immunodeficiency Virus Genome of RT-SHIV

RT-SHIV is a chimera of simian immunodeficiency virus (SIV) containing the reverse transcriptase (RT)-encoding region of human immunodeficiency virus type 1 (HIV-1) within the backbone of SIV(mac239). It has been used in a non-human primate model for studies of non-nucleoside RT inhibitors (NNRTI) a...

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Détails bibliographiques
Auteurs principaux: Wadford, Debra A., Kauffman, Robert C., Deere, Jesse D., Aoki, Scott T., Stanton, Richard A., Higgins, Joanne, Van Rompay, Koen K. A., Villalobos, Andradi, Nettles, James H., Schinazi, Raymond F., Pedersen, Niels C., North, Thomas W.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909041/
https://ncbi.nlm.nih.gov/pubmed/24498008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086997
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