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Variation of Human Immunodeficiency Virus Type-1 Reverse Transcriptase within the Simian Immunodeficiency Virus Genome of RT-SHIV

RT-SHIV is a chimera of simian immunodeficiency virus (SIV) containing the reverse transcriptase (RT)-encoding region of human immunodeficiency virus type 1 (HIV-1) within the backbone of SIV(mac239). It has been used in a non-human primate model for studies of non-nucleoside RT inhibitors (NNRTI) a...

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Bibliographische Detailangaben
Hauptverfasser: Wadford, Debra A., Kauffman, Robert C., Deere, Jesse D., Aoki, Scott T., Stanton, Richard A., Higgins, Joanne, Van Rompay, Koen K. A., Villalobos, Andradi, Nettles, James H., Schinazi, Raymond F., Pedersen, Niels C., North, Thomas W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909041/
https://ncbi.nlm.nih.gov/pubmed/24498008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086997
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