Persistence of viral reservoirs in multiple tissues after antiretroviral therapy suppression in a macaque RT-SHIV model.

Although antiretroviral therapy (ART) can suppress HIV-1 replication sufficiently to eliminate measurable plasma viremia, infected cells remain and ensure viral recrudescence after discontinuation of ART. We used a macaque model of HIV-1/AIDS to evaluate the location of infected cells during ART. Tw...

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Hlavní autoři:	Christopher Kline, Jean Ndjomou, Tamera Franks, Rebecca Kiser, Vicky Coalter, Jeremy Smedley, Michael Piatak, John W Mellors, Jeffrey D Lifson, Zandrea Ambrose
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2013-01-01
Edice:	PLoS ONE
On-line přístup:	https://doi.org/10.1371/journal.pone.0084275
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