The Level of Reverse Transcriptase (RT) in Human Immunodeficiency Virus Type 1 Particles Affects Susceptibility to Nonnucleoside RT Inhibitors but Not to Lamivudine

We investigated the relationship between the level of reverse transcriptase (RT) in human immunodeficiency virus type 1 (HIV-1) particles and susceptibility to nonnucleoside reverse transcriptase inhibitors (NNRTIs). HIV-1 virions containing different active levels of RT were generated. Susceptibili...

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Main Authors: Ambrose, Zandrea, Julias, John G., Boyer, Paul L., KewalRamani, Vineet N., Hughes, Stephen H.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2006
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1395365/
https://ncbi.nlm.nih.gov/pubmed/16474164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.5.2578-2581.2006
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