Genetic Diversity of Simian Immunodeficiency Virus Encoding HIV-1 Reverse Transcriptase Persists in Macaques despite Antiretroviral Therapy

The impact of antiretroviral therapy (ART) on the genetics of simian immunodeficiency virus (SIV) or human immunodeficiency virus (HIV) populations has been incompletely characterized. We analyzed SIV genetic variation before, during, and after ART in a macaque model. Six pigtail macaques were infec...

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Autores principales: Kearney, Mary, Spindler, Jon, Shao, Wei, Maldarelli, Frank, Palmer, Sarah, Hu, Shiu-Lok, Lifson, Jeffrey D., KewalRamani, Vineet N., Mellors, John W., Coffin, John M., Ambrose, Zandrea
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2011
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019993/
https://ncbi.nlm.nih.gov/pubmed/21084490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01701-10
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