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Estimate of effective recombination rate and average selection coefficient for HIV in chronic infection
HIV adaptation to a host in chronic infection is simulated by means of a Monte-Carlo algorithm that includes the evolutionary factors of mutation, positive selection with varying strength among sites, random genetic drift, linkage, and recombination. By comparing two sensitive measures of linkage di...
में बचाया:
| मुख्य लेखकों: | , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
National Academy of Sciences
2011
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3078368/ https://ncbi.nlm.nih.gov/pubmed/21436045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1102036108 |
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