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Estimate of effective recombination rate and average selection coefficient for HIV in chronic infection

HIV adaptation to a host in chronic infection is simulated by means of a Monte-Carlo algorithm that includes the evolutionary factors of mutation, positive selection with varying strength among sites, random genetic drift, linkage, and recombination. By comparing two sensitive measures of linkage di...

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Bibliografski detalji
Glavni autori: Batorsky, Rebecca, Kearney, Mary F., Palmer, Sarah E., Maldarelli, Frank, Rouzine, Igor M., Coffin, John M.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078368/
https://ncbi.nlm.nih.gov/pubmed/21436045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1102036108
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