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Estimate of effective recombination rate and average selection coefficient for HIV in chronic infection
HIV adaptation to a host in chronic infection is simulated by means of a Monte-Carlo algorithm that includes the evolutionary factors of mutation, positive selection with varying strength among sites, random genetic drift, linkage, and recombination. By comparing two sensitive measures of linkage di...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2011
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3078368/ https://ncbi.nlm.nih.gov/pubmed/21436045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1102036108 |
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