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Evolution of Human Immunodeficiency Virus Under Selection and Weak Recombination
To predict emergence of drug resistance in patients undergoing antiretroviral therapy, we study accumulation of preexisting beneficial alleles in a haploid population of N genomes. The factors included in the model are selection with the coefficient s and recombination with the small rate per genome...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Genetics Society of America
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1449738/ https://ncbi.nlm.nih.gov/pubmed/15744057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.029926 |
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