Evolution of the Human Immunodeficiency Virus Envelope Gene Is Dominated by Purifying Selection

The evolution of the human immunodeficiency virus (HIV-1) during chronic infection involves the rapid, continuous turnover of genetic diversity. However, the role of natural selection, relative to random genetic drift, in governing this process is unclear. We tested a stochastic model of genetic dri...

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Autori principali: Edwards, C. T. T., Holmes, E. C., Pybus, O. G., Wilson, D. J., Viscidi, R. P., Abrams, E. J., Phillips, R. E., Drummond, A. J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Copyright © 2006 by the Genetics Society of America 2006
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Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1667091/
https://ncbi.nlm.nih.gov/pubmed/16951087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.052019
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