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Transition between Stochastic Evolution and Deterministic Evolution in the Presence of Selection: General Theory and Application to Virology
We present here a self-contained analytic review of the role of stochastic factors acting on a virus population. We develop a simple one-locus, two-allele model of a haploid population of constant size including the factors of random drift, purifying selection, and random mutation. We consider diffe...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC99023/ https://ncbi.nlm.nih.gov/pubmed/11238990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MMBR.65.1.151-185.2001 |
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