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An evolution-based high-fidelity method of epistasis measurement: Theory and application to influenza

Linkage effects in a multi-locus population strongly influence its evolution. The models based on the traveling wave approach enable us to predict the average speed of evolution and the statistics of phylogeny. However, predicting statistically the evolution of specific sites and pairs of sites in t...

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Pubblicato in:PLoS Pathog
Autori principali: Pedruzzi, Gabriele, Rouzine, Igor M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8248644/
https://ncbi.nlm.nih.gov/pubmed/34153082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009669
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