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Evolutionary footprint of epistasis

Variation of an inherited trait across a population cannot be explained by additive contributions of relevant genes, due to epigenetic effects and biochemical interactions (epistasis). Detecting epistasis in genomic data still represents a significant challenge that requires a better understanding o...

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發表在:PLoS Comput Biol
Main Authors: Pedruzzi, Gabriele, Barlukova, Ayuna, Rouzine, Igor M.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177197/
https://ncbi.nlm.nih.gov/pubmed/30222748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006426
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