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Transition between Stochastic Evolution and Deterministic Evolution in the Presence of Selection: General Theory and Application to Virology

We present here a self-contained analytic review of the role of stochastic factors acting on a virus population. We develop a simple one-locus, two-allele model of a haploid population of constant size including the factors of random drift, purifying selection, and random mutation. We consider diffe...

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Bibliografski detalji
Glavni autori: Rouzine, I. M., Rodrigo, A., Coffin, J. M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2001
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC99023/
https://ncbi.nlm.nih.gov/pubmed/11238990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MMBR.65.1.151-185.2001
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