Origin of Rebound Plasma HIV Includes Cells with Identical Proviruses That Are Transcriptionally Active before Stopping of Antiretroviral Therapy

Understanding the origin of HIV variants during viral rebound may provide insight into the composition of the HIV reservoir and has implications for the design of curative interventions. HIV single-genome sequences were obtained from 10 AIDS Clinical Trials Group participants who underwent analytic...

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Vydáno v:J Virol
Hlavní autoři: Kearney, Mary F., Wiegand, Ann, Shao, Wei, Coffin, John M., Mellors, John W., Lederman, Michael, Gandhi, Rajesh T., Keele, Brandon F., Li, Jonathan Z.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719635/
https://ncbi.nlm.nih.gov/pubmed/26581989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02139-15
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