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Quantification of HIV-1 latency reversal in resting CD4(+) T cells from patients on suppressive antiretroviral therapy
Reversal of proviral latency is being pursued as a curative strategy for HIV-1 infection. Recent clinical studies of in vivo administration of the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA; vorinostat) show increases in unspliced cellular HIV-1 RNA levels in resting CD4(+)...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4024870/ https://ncbi.nlm.nih.gov/pubmed/24706775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1402873111 |
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