Antiretroviral Intensification and Valproic Acid Lack Sustained Effect on Residual HIV-1 Viremia or Resting CD4+ Cell Infection

BACKGROUND: Human immunodeficiency virus (HIV) infection that persists despite antiretroviral therapy (ART) is a daunting problem. Given the limited evidence that resting CD4+ T cell infection (RCI) is affected by the histone deacetylase (HDAC) inhibitor valproic acid (VPA), we measured the stabilit...

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Autori principali: Archin, Nancie M., Cheema, Manzoor, Parker, Daniel, Wiegand, Ann, Bosch, Ronald J., Coffin, John M., Eron, Joseph, Cohen, Myron, Margolis, David M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826423/
https://ncbi.nlm.nih.gov/pubmed/20186346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009390
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