Clonal Sequences Recovered from Plasma from Patients with Residual HIV-1 Viremia and on Intensified Antiretroviral Therapy Are Identical to Replicating Viral RNAs Recovered from Circulating Resting CD4(+) T Cells

Despite successful antiretroviral therapy (ART), low-level viremia (LLV) may be intermittently detected in most HIV-infected patients. Longitudinal blood plasma and resting CD4(+) T cells were obtained from two patients on suppressive ART to investigate the source of LLV. Single-genome sequencing of...

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Main Authors: Anderson, Jeffrey A., Archin, Nancie M., Ince, William, Parker, Daniel, Wiegand, Ann, Coffin, John M., Kuruc, JoAnn, Eron, Joseph, Swanstrom, Ronald, Margolis, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126162/
https://ncbi.nlm.nih.gov/pubmed/21367910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00284-11
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