Development of an In Vivo Assay To Identify Structural Determinants in Murine Leukemia Virus Reverse Transcriptase Important for Fidelity

Por Halvas, Elias K., Svarovskaia, Evguenia S., Pathak, Vinay K.
Publicado em 2000

Role of Murine Leukemia Virus Reverse Transcriptase Deoxyribonucleoside Triphosphate-Binding Site in Retroviral Replication and In Vivo Fidelity

Por Halvas, Elias K., Svarovskaia, Evguenia S., Pathak, Vinay K.
Publicado em 2000

Wild-Type and YMDD Mutant Murine Leukemia Virus Reverse Transcriptases Are Resistant to 2′,3′-Dideoxy-3′-Thiacytidine

Por Halvas, Elias K., Svarovskaia, Evguenia S., Freed, Eric O., Pathak, Vinay K.
Publicado em 2000

Sensitive Phenotypic Detection of Minor Drug-Resistant Human Immunodeficiency Virus Type 1 Reverse Transcriptase Variants

Por Nissley, Dwight V., Halvas, Elias K., Hoppman, Nicole L., Garfinkel, David J., Mellors, John W., Strathern, Jeffrey N.
Publicado em 2005

Performance of Celera RUO integrase resistance assay across multiple HIV-1 subtypes

Por Wallis, Carole L, Viana, Raquel V, Saravanan, Shanmugam, de Jesus, Carlos Silva, Zeh, Clement, Halvas, Elias K, Mellors, John W
Publicado no J Virol Methods (2016)

Ex vivo activation of CD4(+) T-cells from donors on suppressive ART can lead to sustained production of infectious HIV-1 from a subset of infected cells

Por Bui, John K., Halvas, Elias K., Fyne, Elizabeth, Sobolewski, Michele D., Koontz, Dianna, Shao, Wei, Luke, Brian, Hong, Feiyu F., Kearney, Mary F., Mellors, John W.
Publicado no PLoS Pathog (2017)

Low Frequency NNRTI-Resistant Variants Contribute to Failure of Efavirenz-Containing Regimens in Treatment-Experienced Patients

Por Halvas, Elias K., Wiegand, Ann, Boltz, Valerie F., Kearney, Mary, Nissley, Dwight, Wantman, Michael, Hammer, Scott M., Palmer, Sarah, Vaida, Florin, Coffin, John M., Mellors, John W.
Publicado em 2010

Multiple, Linked Human Immunodeficiency Virus Type 1 Drug Resistance Mutations in Treatment-Experienced Patients Are Missed by Standard Genotype Analysis

Por Palmer, Sarah, Kearney, Mary, Maldarelli, Frank, Halvas, Elias K., Bixby, Christian J., Bazmi, Holly, Rock, Diane, Falloon, Judith, Davey, Richard T., Dewar, Robin L., Metcalf, Julia A., Hammer, Scott, Mellors, John W., Coffin, John M.
Publicado em 2005

Frequency of Antiretroviral Resistance Mutations among Infants Exposed to Single-Dose Nevirapine and Short Course Maternal Antiretroviral Regimens: ACTG A5207

Por Hitti, Jane, Halvas, Elias K, Zheng, Lu, Panousis, Constantinos G, Kabanda, Joseph, Taulo, Frank, Kumarasamy, Nagalingeswaran, Pape, Jean William, Lalloo, Umesh, Sprenger, Heather, Klingman, Karin L, Chan, Ellen S, McMahon, Deborah, Mellors, John W
Publicado no J AIDS Clin Res (2014)

Role of low-frequency HIV-1 variants in failure of nevirapine-containing antiviral therapy in women previously exposed to single-dose nevirapine

Por Boltz, Valerie F., Zheng, Yu, Lockman, Shahin, Hong, Feiyu, Halvas, Elias K., McIntyre, James, Currier, Judith S., Chibowa, Margret C., Kanyama, Cecelia, Nair, Apsara, Owino-Ong'or, Willis, Hughes, Michael, Coffin, John M., Mellors, John W.
Publicado em 2011

Greater Suppression of Nevirapine Resistance With 21- vs 7-Day Antiretroviral Regimens After Intrapartum Single-Dose Nevirapine for Prevention of Mother-to-Child Transmission of HI...

Por McMahon, Deborah K., Zheng, Lu, Hitti, Jane, Chan, Ellen S., Halvas, Elias K., Hong, Feiyu, Kabanda, Joseph, Taulo, Frank, Kumarasamy, Nagalingeswaran, Bonhomme, Jerry, Wallis, Carole L., Klingman, Karin L., Hughes, Michael D., Mellors, John W.
Publicado em 2013

Blinded, Multicenter Comparison of Methods To Detect a Drug-Resistant Mutant of Human Immunodeficiency Virus Type 1 at Low Frequency

Por Halvas, Elias K., Aldrovandi, Grace M., Balfe, Peter, Beck, Ingrid A., Boltz, Valerie F., Coffin, John M., Frenkel, Lisa M., Hazelwood, J. Darren, Johnson, Victoria A., Kearney, Mary, Kovacs, Andrea, Kuritzkes, Daniel R., Metzner, Karin J., Nissley, Dwight V., Nowicki, Marek, Palmer, Sarah, Ziermann, Rainer, Zhao, Richard Y., Jennings, Cheryl L., Bremer, James, Brambilla, Don, Mellors, John W.
Publicado em 2006

Clonally expanded CD4(+) T cells can produce infectious HIV-1 in vivo

Por Simonetti, Francesco R., Sobolewski, Michele D., Fyne, Elizabeth, Shao, Wei, Spindler, Jonathan, Hattori, Junko, Anderson, Elizabeth M., Watters, Sarah A., Hill, Shawn, Wu, Xiaolin, Wells, David, Su, Li, Luke, Brian T., Halvas, Elias K., Besson, Guillaume, Penrose, Kerri J., Yang, Zhiming, Kwan, Richard W., Van Waes, Carter, Uldrick, Thomas, Citrin, Deborah E., Kovacs, Joseph, Polis, Michael A., Rehm, Catherine A., Gorelick, Robert, Piatak, Michael, Keele, Brandon F., Kearney, Mary F., Coffin, John M., Hughes, Stephen H., Mellors, John W., Maldarelli, Frank
Publicado no Proc Natl Acad Sci U S A (2016)

Low-Frequency Nevirapine (NVP)–Resistant HIV-1 Variants Are Not Associated With Failure of Antiretroviral Therapy in Women Without Prior Exposure to Single-Dose NVP

Por Boltz, Valerie F., Bao, Yajing, Lockman, Shahin, Halvas, Elias K., Kearney, Mary F., McIntyre, James A., Schooley, Robert T., Hughes, Michael D., Coffin, John M., Mellors, John W., Zwickl, Beth, Mutuluuza, CissyKityo, Kaseba, Christine, Maponga, Charles C., Watts, Heather, Kuritzkes, Daniel, Campbell, Thomas B., Kidd-Freeman, Lynn, Carten, Monica, Hitti, Jane, Marovich, Mary, Mugyenyi, Peter N., Rwambuya, Sandra, Sanne, Ian M., Putnam, Beverly, Marcus, Cheryl, Wester, Carolyn, DiFrancesco, Robin, Halvas, Elias, Beddison, Annie, Lehrman, Sandra, Aweeka, Francesca, Dong, Betty, Ziba, Peter Ndhleni, Saag, Michael S., Holmes, William C., Hammer, Scott M.
Publicado em 2014