Low Frequency NNRTI-Resistant Variants Contribute to Failure of Efavirenz-Containing Regimens in Treatment-Experienced Patients

BACKGROUND: The contribution of low frequency drug-resistant HIV-1 variants to failure of antiretroviral therapy is not well-defined in treatment-experienced patients. OBJECTIVE: We sought to detect minor non-nucleoside reverse transcriptase inhibitor (NNRTI)-resistant variants at the onset of multi...

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Main Authors: Halvas, Elias K., Wiegand, Ann, Boltz, Valerie F., Kearney, Mary, Nissley, Dwight, Wantman, Michael, Hammer, Scott M., Palmer, Sarah, Vaida, Florin, Coffin, John M., Mellors, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835354/
https://ncbi.nlm.nih.gov/pubmed/20102272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/650542
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