Novel Mutations in a Tissue Culture-Adapted Hepatitis C Virus Strain Improve Infectious-Virus Stability and Markedly Enhance Infection Kinetics

Por Pokrovskii, Maria V., Bush, Caroline O., Beran, Rudolf K. F., Robinson, Margaret F., Cheng, Guofeng, Tirunagari, Neeraj, Fenaux, Martijn, Greenstein, Andrew E., Zhong, Weidong, Delaney, William E., Paulson, Matthew S.
Publicado em 2011

Structural and Regulatory Elements of HCV NS5B Polymerase – β-Loop and C-Terminal Tail – Are Required for Activity of Allosteric Thumb Site II Inhibitors

Por Boyce, Sarah E., Tirunagari, Neeraj, Niedziela-Majka, Anita, Perry, Jason, Wong, Melanie, Kan, Elaine, Lagpacan, Leanna, Barauskas, Ona, Hung, Magdeleine, Fenaux, Martijn, Appleby, Todd, Watkins, William J., Schmitz, Uli, Sakowicz, Roman
Publicado em 2014

Inhibition of Hepatitis C Virus Replication by GS-6620, a Potent C-Nucleoside Monophosphate Prodrug

Por Feng, Joy Y., Cheng, Guofeng, Perry, Jason, Barauskas, Ona, Xu, Yili, Fenaux, Martijn, Eng, Stacey, Tirunagari, Neeraj, Peng, Betty, Yu, Mei, Tian, Yang, Lee, Yu-Jen, Stepan, George, Lagpacan, Leanna L., Jin, Debi, Hung, Magdeleine, Ku, Karin S., Han, Bin, Kitrinos, Kathryn, Perron, Michel, Birkus, Gabriel, Wong, Kelly A., Zhong, Weidong, Kim, Choung U., Carey, Anne, Cho, Aesop, Ray, Adrian S.
Publicado em 2014

Optimization of Pharmacokinetics through Manipulation of Physicochemical Properties in a Series of HCV Inhibitors

Por Lazerwith, Scott E., Bahador, Gina, Canales, Eda, Cheng, Guofeng, Chong, Lee, Clarke, Michael O., Doerffler, Edward, Eisenberg, Eugene J., Hayes, Jaclyn, Lu, Bing, Liu, Qi, Matles, Mike, Mertzman, Michael, Mitchell, Michael L., Morganelli, Philip, Murray, Bernard P., Robinson, Margaret, Strickley, Robert G., Tessler, Megan, Tirunagari, Neeraj, Wang, Jianhong, Wang, Yujin, Zhang, Jennifer R., Zheng, Xubin, Zhong, Weidong, Watkins, William J.
Publicado em 2011