A Cell-Based Strategy To Assess Intrinsic Inhibition Efficiencies of HIV-1 Reverse Transcriptase Inhibitors

Por Abram, Michael E., Tsiang, Manuel, White, Kirsten L., Callebaut, Christian, Miller, Michael D.
Publicado no Antimicrob Agents Chemother (2015)

Catalytically-active complex of HIV-1 integrase with a viral DNA substrate binds anti-integrase drugs

Por Alian, Akram, Griner, Sarah L., Chiang, Vicki, Tsiang, Manuel, Jones, Gregg, Birkus, Gabriel, Geleziunas, Romas, Leavitt, Andrew D., Stroud, Robert M.
Publicado em 2009

Preclinical Evaluation of GS-9160, a Novel Inhibitor of Human Immunodeficiency Virus Type 1 Integrase

Por Jones, Gregg S., Yu, Fang, Zeynalzadegan, Ameneh, Hesselgesser, Joseph, Chen, Xiaowu, Chen, James, Jin, Haolun, Kim, Choung U., Wright, Matthew, Geleziunas, Romas, Tsiang, Manuel
Publicado em 2009

Affinities between the Binding Partners of the HIV-1 Integrase Dimer-Lens Epithelium-derived Growth Factor (IN Dimer-LEDGF) Complex

Por Tsiang, Manuel, Jones, Gregg S., Hung, Magdeleine, Mukund, Susmith, Han, Bin, Liu, Xiaohong, Babaoglu, Kerim, Lansdon, Eric, Chen, Xiaowu, Todd, Jacob, Cai, Terrence, Pagratis, Nikos, Sakowicz, Roman, Geleziunas, Romas
Publicado em 2009

New Class of HIV-1 Integrase (IN) Inhibitors with a Dual Mode of Action

Por Tsiang, Manuel, Jones, Gregg S., Niedziela-Majka, Anita, Kan, Elaine, Lansdon, Eric B., Huang, Wayne, Hung, Magdeleine, Samuel, Dharmaraj, Novikov, Nikolai, Xu, Yili, Mitchell, Michael, Guo, Hongyan, Babaoglu, Kerim, Liu, Xiaohong, Geleziunas, Romas, Sakowicz, Roman
Publicado em 2012

Study of Marine Natural Products Including Resorcyclic Acid Lactones from Humicola fuscoatra That Reactivate Latent HIV-1 Expression in an in Vitro Model of Central Memory CD4+ T C...

Por Mejia, Eric J., Loveridge, Steven T., Stepan, George, Tsai, Angela, Jones, Gregg S., Barnes, Tiffany, White, Kimberly N., Drašković, Marija, Tenney, Karen, Tsiang, Manuel, Geleziunas, Romas, Cihlar, Tomas, Pagratis, Nikos, Tian, Yang, Yu, Helen, Crews, Phillip
Publicado em 2014

Antiviral Activity of Bictegravir (GS-9883), a Novel Potent HIV-1 Integrase Strand Transfer Inhibitor with an Improved Resistance Profile

Por Tsiang, Manuel, Jones, Gregg S., Goldsmith, Joshua, Mulato, Andrew, Hansen, Derek, Kan, Elaine, Tsai, Luong, Bam, Rujuta A., Stepan, George, Stray, Kirsten M., Niedziela-Majka, Anita, Yant, Stephen R., Yu, Helen, Kukolj, George, Cihlar, Tomas, Lazerwith, Scott E., White, Kirsten L., Jin, Haolun
Publicado no Antimicrob Agents Chemother (2016)